Bio X Cell社 – 免疫チェックポイント関連商品

Bio X Cell社の免疫チェックポイント関連商品をご紹介します。

全商品の情報はこちらのページをご参考ください。

免疫チェックポイントとは?

免疫チェックポイントは、免疫システムが自己抗原を無差別に攻撃することを防ぐ免疫システムの制御機構です。これは、自己免疫疾患を防止することに極めて重要である一方で、免疫システムが、がんの死滅や抑制において無力化することの原因となります。

腫瘍細胞はある免疫チェックポイント経路を主要な免疫耐性のメカニズムとして、特に腫瘍抗原に特異的なT細胞に対して、利用しています。免疫チェックポイントの大半はリガンド-受容体の相互作用によって開始されるため、抗体によって容易に阻害されます。

免疫チェックポイントの阻害は抗腫瘍活性を回復させ、治癒的な抗腫瘍免疫を活性化させる最も有望な方法です。

Bio X Cell社は、マウスの免疫チェックポイントタンパク質を標的とする非常に多くの抗体をご提供します。

関連ページ

Bio X Cell社 – PD-1およびPD-L1マウスモノクローナル抗体の比較

商品リスト

InVivoMab


BE0015-1InVivoMAb anti-mouse CD281/5/25/50/100 mg
Clone37.51IsotypeSyrian Hamster IgG2
Applicationin vitro T cell stimulation/activation, in vivo CD28 blockade
RecommendedIsotype Control: BE0087 Dilution Buffer: IPT060
BE0015-5InVivoMAb anti-mouse CD281/5/25/50/100 mg
ClonePV-1IsotypeArmenian Hamster IgG, κ
Applicationin vitro T cell stimulation/activation
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0016-2InVivoMAb anti-mouse CD401/5/25/50/100 mg
CloneFGK4.5/FGK45IsotypeRat IgG2a
Applicationin vivo CD40 activation, in vitro B cell stimulation/activation
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0017-1InVivoMAb anti-mouse CD40L (CD154)1/5/25/50/100 mg
CloneMR-1IsotypeArmenian Hamster IgG
Applicationin vivo blocking of CD40/CD40L signaling, in vitro blocking of CD40/CD40L signaling, Western blot
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0019-1InVivoMAb anti-human CD471/5/25/50/100 mg
CloneB6.H12IsotypeMouse IgG1, κ
Applicationin vitro CD47 neutralization, in vivo CD47 neutralization in human tumor xenograft models or humanized mice, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0022InVivoMAb anti-mouse CD701/5/25/50/100 mg
CloneFR70IsotypeRat IgG2b, κ
Applicationin vivo CD70 blockade, in vitro CD70 blockade, Flow cytometry
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0070
BE0024InVivoMAb anti-mouse CD80 (B7-1)1/5/25/50/100 mg
Clone16-10A1IsotypeArmenian Hamster IgG2
Applicationin vivo CD80 blockade, Flow cytometry
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0080
BE0025InVivoMAb anti-mouse CD86 (B7-2)1/5/25/50/100 mg
CloneGL-1IsotypeRat IgG2a, κ
Applicationin vivo CD86 blockade, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0028InVivoMAb anti-mouse ICOSL (CD275)1/5/25/50/100 mg
CloneHK5.3IsotypeRat IgG2a, κ
Applicationin vivo ICOSL neutralization
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0031InVivoMAb anti-mouse OX40 (CD134)1/5/25/50/100 mg
CloneOX-86IsotypeRat IgG1, κ
Applicationin vivo OX40 activation, in vitro OX40 activation, Western blot
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0070
BE0032InVivoMAb anti-mouse CTLA-4 (CD152)1/5/25/50/100 mg
CloneUC10-4F10-11IsotypeArmenian Hamster IgG
Applicationin vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Flow cytometry, Western blot
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0065
BE0033-1InVivoMAb anti-mouse OX40L (CD134L)1/5/25/50/100 mg
CloneRM134LIsotypeRat IgG2b, κ
Applicationin vivo blocking of OX40/OX40L signaling, in vitro OX40L neutralization
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0070
BE0033-2InVivoMAb anti-mouse PD-1 (CD279)1/5/25/50/100 mg
CloneJ43IsotypeArmenian Hamster IgG
Applicationin vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Western blot
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0065
BE0040InVivoMAb anti-rat CD281/5/25/50/100 mg
CloneJJ319IsotypeMouse IgG1, κ
Applicationin vitro T cell stimulation/activation, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0059InVivoMAb anti-mouse ICOS1/5/25/50/100 mg
Clone7E.17G9IsotypeRat IgG2b, κ
Applicationin vivo blocking of ICOS/ICOSL signaling, Flow cytometry
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0080
BE0063InVivoMAb anti-mouse GITR1/5/25/50/100 mg
CloneDTA-1IsotypeRat IgG2b, λ
Applicationin vivo GITR stimulation
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0070
BE0099InVivoMAb recombinant CTLA-4-Ig (hum/hum)1/5/25/50/100 mg
CloneCTLA-4-Ig (hum/hum)Isotype
RecommendedIsotype Control: BE0096 Dilution Buffer: IP0070
BE0101InVivoMAb anti-mouse PD-L1 (B7-H1)1/5/25/50/100 mg
Clone10F.9G2™IsotypeRat IgG2b, κ
Applicationin vivo PD-L1 blockade, Immunofluorescence, Immunohistochemistry (frozen), Flow cytometry, Western blot
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0065
BE0110InVivoMAb anti-mouse 4-1BBL (CD137L)1/5/25/50/100 mg
CloneTKS-1IsotypeRat IgG2a, κ
Applicationin vivo 4-1BBL blockade, ELISA
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0112InVivoMAb anti-mouse PD-L2 (B7-DC)1/5/25/50/100 mg
CloneTY25IsotypeRat IgG2a, κ
Applicationin vivo PD-L2 blockade, in vitro PD-L2 blockade, Immunohistochemistry (frozen), Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0113InVivoMAb anti-mouse TIM-1 (CD365)1/5/25/50/100 mg
CloneRMT1-10IsotypeRat IgG2a, κ
Applicationin vivo TIM-1 blockade
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0115InVivoMAb anti-mouse TIM-3 (CD366)1/5/25/50/100 mg
CloneRMT3-23IsotypeRat IgG2a, κ
Applicationin vivo TIM-3 neutralization, in vitro TIM-3 blocking, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0124InVivoMAb anti-mouse CD276 (B7-H3)1/5/25/50/100 mg
CloneMJ18IsotypeRat IgG1, κ
Applicationin vivo B7-H3 blockade, Flow cytometry
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0070
BE0131InVivoMAb anti-mouse CTLA-4 (CD152)1/5/25/50/100 mg
Clone9H10IsotypeSyrian Hamster IgG
Applicationin vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Western blot
RecommendedIsotype Control: BE0087 Dilution Buffer: IP0070
BE0132InVivoMAb anti-mouse BTLA (CD272)1/5/25/50/100 mg
Clone6A6IsotypeArmenian Hamster IgG, κ
Applicationin vivo BTLA stimulation, in vivo BTLA blockade
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0134InVivoMAb anti-mouse CD80 (B7-1)1/5/25/50/100 mg
Clone1G10IsotypeRat IgG2a, κ
Applicationin vivo CD80 blockade, Affinity chromatography
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0146InVivoMAb anti-mouse PD-1 (CD279)1/5/25/50/100 mg
CloneRMP1-14IsotypeRat IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0153InVivoMAb anti-mouse BTLA (CD272)1/5/25/50/100 mg
ClonePK18.6IsotypeRat IgG1, κ
Applicationin vivo stimulation of BTLA, in vitro stimulation of BTLA, Flow cytometry
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0070
BE0164InVivoMAb anti-mouse CTLA-4 (CD152)1/5/25/50/100 mg
Clone9D9IsotypeMouse IgG2b
Applicationin vivo CTLA-4 neutralization, Western blot
RecommendedIsotype Control: BE0086 Dilution Buffer: IP0070
BE0169InVivoMAb anti-mouse 4-1BB (CD137)1/5/25/50/100 mg
CloneLOB12.3IsotypeRat IgG1, κ
Applicationin vivo activation of 4-1BB
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0080
BE0174InVivoMAb anti-mouse LAG-31/5/25/50/100 mg
CloneC9B7WIsotypeRat IgG1, κ
Applicationin vivo LAG-3 neutralization, in vitro LAG-3 neutralization, Flow cytometry, Western blot
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0070
BE0187InVivoMAb anti-rat CD80 (B7-1)1/5/25/50/100 mg
Clone3H5IsotypeMouse IgG1, κ
Applicationin vitro CD80 blockade, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0188InVivoMAb anti-human PD-1 (CD279)1/5/25/50/100 mg
CloneJ116IsotypeMouse IgG1, κ
Applicationin vitro PD-1 neutralization, in vivo PD-1 blockade in humanized mice
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0189InVivoMAb anti-human CD401/5/25/50/100 mg
CloneG28.5IsotypeMouse IgG1, κ
Applicationin vitro CD40 stimulation, Functional assays, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0190InVivoMAb anti-human CTLA-4 (CD152)1/5/25/50/100 mg
CloneBN13IsotypeMouse IgG2a, κ
Applicationin vitro CTLA-4 neutralization, Flow cytometry
RecommendedIsotype Control: BE0085 Dilution Buffer: IP0070
BE0193InVivoMAb anti-human PD-1 (CD279)1/5/25/50/100 mg
CloneJ110IsotypeMouse IgG1, κ
Applicationin vivo PD-1 blockade in humanized mice, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0196InVivoMAb anti-mouse BTLA (CD272)1/5/25/50/100 mg
ClonePJ196IsotypeMouse IgG1
Applicationin vivo BTLA blockade, in vitro T cell stimulation/activation, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0218InVivoMAb anti-mouse Galectin-91/5/25/50/100 mg
CloneRG9-1IsotypeRat IgG2b, κ
Applicationin vivo Galectin-9 blockade in vitro Galectin-9 blockade
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0070
BE0239InVivoMAb anti-mouse 4-1BB (CD137)1/5/25/50/100 mg
Clone3H3IsotypeRat IgG2a
Applicationin vivo 4-1BB stimulation, in vitro 4-1BB stimulation
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0248InVivoMAb anti-human CD281/5/25/50/100 mg
Clone9.3IsotypeMouse IgG2a
Applicationin vitro T cell stimulation/activation
RecommendedIsotype Control: BE0085 Dilution Buffer: IP0070
BE0273InVivoMAb anti-mouse PD-1 (CD279)1/5/25/50/100 mg
Clone29F.1A12™IsotypeRat IgG2a
Applicationin vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Immunohistochemistry (frozen), Immunofluorescence, Western blot, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0274InVivoMAb anti-mouse TIGIT1/5/25/50/100 mg
Clone1G9IsotypeMouse IgG1, κ
Applicationin vivo TIGIT stimulation, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0285InVivoMAb anti-human PD-L1 (B7-H1)1/5/25/50/100 mg
Clone29E.2A3IsotypeMouse IgG2b, κ
Applicationin vitro PD-L1 blockade, Functional assays, Immunohistochemistry (frozen), Flow cytometry
RecommendedIsotype Control: BE0086 Dilution Buffer: IP0070
BE0289InVivoMAb anti-mouse TIM-1 (CD365)1/5/25/50/100 mg
Clone3B3IsotypeRat IgG2a, κ
Applicationin vivo TIM-1 activation, in vitro T cell stimulation/activation, Functional assays, ELISA, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0291InVivoMAb anti-human/monkey CD281/5/25/50/100 mg
CloneCD28.2IsotypeMouse IgG1, κ
Applicationin vitro T cell stimulation/activation, Immunoprecipitation, Flow cytometry, Immunohistochemistry (frozen)
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0292InVivoMAb anti-human/monkey CD40L (CD154)1/5/25/50/100 mg
Clone5C8IsotypeMouse IgG2a
Applicationin vitro blocking of CD40/CD40L signaling, in vivo blocking of CD40/CD40L signaling, Immunoprecipitation, Flow cytometry
RecommendedIsotype Control: BE0085 Dilution Buffer: IP0070
BE0296InVivoMAb anti-mouse 4-1BB (CD137)1/5/25/50/100 mg
Clone17B5IsotypeSyrian Hamster IgG
Applicationin vitro 4-1BB blockade, Flow cytometry
RecommendedIsotype Control: BE0087 Dilution Buffer: IP0070
BE0299InVivoMAb anti-mouse CD200 (OX2)1/5/25/50/100 mg
CloneOX-90IsotypeRat IgG2a, κ
Applicationin vivo CD200 blockade, in vitro CD200 blockade, Immunohistochemistry (frozen), Immunofluorescence, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0310InVivoMAb anti-mouse VISTA1/5/25/50/100 mg
Clone13F3IsotypeArmenian Hamster IgG
Applicationin vivo blocking of VISTA signaling, in vitro blocking of VISTA signaling
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0314InVivoMAb anti-mouse TIM-1 (CD365)1/5/25/50/100 mg
Clone3D10IsotypeRat IgG1, κ
Applicationin vivo TIM-1 blockade, in vitro TIM-1 blockade
RecommendedIsotype Control: BE0088 Dilution Buffer: IP0070
BE0328InVivoMAb anti-mouse CD281/5/25/50/100 mg
CloneD665IsotypeMouse IgG1, κ
Applicationin vivo T cell stimulation/activation, in vitro T cell stimulation/activation
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0332InVivoMAb anti-mouse FGL-11/5/25/50/100 mg
Clone177R4IsotypeRat IgG2a, κ
Applicationin vivo FGL-1 blockade, in vitro FGL-1 blockade, Flow cytometry, Immunohistochemistry (paraffin)
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0348InVivoMAb anti-mouse CD271/5/25/50/100 mg
CloneRM27-3E5IsotypeRat IgG2a, κ
Applicationin vivo CD27 stimulation, in vitro CD27 stimulation, Immunoprecipitation, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0353InVivoMAb anti-mouse/human/rat/monkey ICOS (CD278)1/5/25/50/100 mg
CloneC398.4AIsotypeArmenian Hamster IgG
Applicationin vitro T cell stimulation/activation, Flow cytometry, Immunoprecipitation
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0361InVivoMAb anti-mouse PD-L1 (B7-H1)1/5/25/50/100 mg
Clone10F.2H11IsotypeRat IgG2b, κ
Applicationin vivo blocking of PD-L1/CD80 (B7-1) interactions, in vitro blocking of PD-L1/CD80 (B7-1) interactions, ELISA, Flow cytometry
RecommendedIsotype Control: BE0090 Dilution Buffer: IP0070
BE0364InVivoMAb anti-mouse BTLA (CD272)1/5/25/50/100 mg
CloneHMBT-6B2IsotypeArmenian Hamster IgG
Applicationin vivo BTLA blockade, Flow cytometry
RecommendedIsotype Control: BE0091 Dilution Buffer: IP0070
BE0365InVivoMAb anti-mouse CD80 (B7-1)1/5/25/50/100 mg
CloneRM80IsotypeRat IgG2a
Applicationin vivo CD80 blockade, in vitro CD80 blockade, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IP0070
BE0372InVivoMAb anti-mouse osteopontin (SPP1)1/5/25/50/100 mg
Clone100D3IsotypeMouse IgG2c, κ
Applicationin vivo OPN neutralization, in vitro OPN neutralization, ELISA
RecommendedIsotype Control: BE0366 Dilution Buffer: IP0070
BE0373InVivoMAb anti-mouse osteopontin (SPP1)1/5/25/50/100 mg
Clone103D6IsotypeMouse IgG2c, κ
Applicationin vivo OPN neutralization, in vitro OPN neutralization, ELISA
RecommendedIsotype Control: BE0366 Dilution Buffer: IP0070
BE0382InVivoMAb anti-mouse/human/rat osteopontin (SPP1)1/5/25/50/100 mg
CloneMPIIIB10IsotypeMouse IgG1, κ
Applicationin vivo OPN neutralization, in vitro OPN neutralization, Immunohistochemistry (paraffin), Western blot
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0387InVivoMAb anti-mouse/human phosphorylated PD-1 (CD279)1/5/25/50/100 mg
Clone407.6G12IsotypeMouse IgG2a, κ
ApplicationWestern Blot, Flow Cytometry
RecommendedIsotype Control: BE0085 Dilution Buffer: IP0070
BE0390InVivoMAb anti-canine PD-L1 (B7-H1)1/5/25/50/100 mg
CloneJC071IsotypeMouse IgG1, κ
Applicationin vitro PD-L1 blockade, Functional assays, Western blot, Flow cytometry
RecommendedIsotype Control: BE0083 Dilution Buffer: IP0070
BE0400InVivoMAb anti-mouse RGMb1/5/25/50/100 mg
Clone307.9D1IsotypeRat IgG2a, κ
Applicationin vivo RGMb blockade, ELISA, Flow cytometry
RecommendedIsotype Control: BE0089 Dilution Buffer: IPT060

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InVivoPlus


BP0016-2InVivoPlus anti-mouse CD405/25/50/100 mg
CloneFGK4.5/FGK45IsotypeRat IgG2a
Applicationin vivo CD40 activation, in vitro B cell stimulation/activation
RecommendedIsotype Control: BP0089 Dilution Buffer: IP0070
BP0017-1InVivoPlus anti-mouse CD40L (CD154)5/25/50/100 mg
CloneMR-1IsotypeArmenian Hamster IgG
Applicationin vivo blocking of CD40/CD40L signaling, in vitro blocking of CD40/CD40L signaling, Western blot
RecommendedIsotype Control: BP0091 Dilution Buffer: IP0070
BP0031InVivoPlus anti-mouse OX40 (CD134)5/25/50/100 mg
CloneOX-86IsotypeRat IgG1, κ
Applicationin vivo OX40 activation, in vitro OX40 activation, Western blot
RecommendedIsotype Control: BP0088 Dilution Buffer: IP0070
BP0032InVivoPlus anti-mouse CTLA-4 (CD152)5/25/50/100 mg
CloneUC10-4F10-11IsotypeArmenian Hamster IgG
Applicationin vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Flow cytometry, Western blot
RecommendedIsotype Control: BP0091 Dilution Buffer: IP0065
BP0033-2InVivoPlus anti-mouse PD-1 (CD279)5/25/50/100 mg
CloneJ43IsotypeArmenian Hamster IgG
Applicationin vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Western blot
RecommendedIsotype Control: BP0091 Dilution Buffer: IP0065
BP0063InVivoPlus anti-mouse GITR5/25/50/100 mg
CloneDTA-1IsotypeRat IgG2b, λ
Applicationin vivo GITR stimulation
RecommendedIsotype Control: BP0090 Dilution Buffer: IP0070
BP0099InVivoPlus recombinant CTLA-4-Ig (hum/hum)5/25/50/100 mg
CloneCTLA-4-Ig (hum/hum)Isotype
RecommendedDilution Buffer: IP0070
BP0101InVivoPlus anti-mouse PD-L1 (B7-H1)5/25/50/100 mg
Clone10F.9G2™IsotypeRat IgG2b, κ
Applicationin vivo PD-L1 blockade, Immunofluorescence, Immunohistochemistry (frozen), Flow cytometry, Western blot
RecommendedIsotype Control: BP0090 Dilution Buffer: IP0065
BP0115InVivoPlus anti-mouse TIM-3 (CD366)5/25/50/100 mg
CloneRMT3-23IsotypeRat IgG2a, κ
Applicationin vivo TIM-3 neutralization, in vitro TIM-3 blocking, Flow cytometry
RecommendedIsotype Control: BP0089 Dilution Buffer: IP0070
BP0131InVivoPlus anti-mouse CTLA-4 (CD152)5/25/50/100 mg
Clone9H10IsotypeSyrian Hamster IgG
Applicationin vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Western blot
RecommendedIsotype Control: BP0087 Dilution Buffer: IP0070
BP0146InVivoPlus anti-mouse PD-1 (CD279)5/25/50/100 mg
CloneRMP1-14IsotypeRat IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling
RecommendedIsotype Control: BP0089 Dilution Buffer: IP0070
BP0164InVivoPlus anti-mouse CTLA-4 (CD152)5/25/50/100 mg
Clone9D9IsotypeMouse IgG2b
Applicationin vivo CTLA-4 neutralization, Western blot
RecommendedIsotype Control: BP0086 Dilution Buffer: IP0070
BP0169InVivoPlus anti-mouse 4-1BB (CD137)5/25/50/100 mg
CloneLOB12.3IsotypeRat IgG1, κ
Applicationin vivo activation of 4-1BB
RecommendedIsotype Control: BP0088 Dilution Buffer: IP0080
BP0174InVivoPlus anti-mouse LAG-35/25/50/100 mg
CloneC9B7WIsotypeRat IgG1, κ
Applicationin vivo LAG-3 neutralization, in vitro LAG-3 neutralization, Flow cytometry, Western blot
RecommendedIsotype Control: BP0088 Dilution Buffer: IP0070
BP0239InVivoPlus anti-mouse 4-1BB (CD137)5/25/50/100 mg
Clone3H3IsotypeRat IgG2a
Applicationin vivo 4-1BB stimulation, in vitro 4-1BB stimulation
RecommendedIsotype Control: BP0089 Dilution Buffer: IP0070
BP0273InVivoPlus anti-mouse PD-1 (CD279)5/25/50/100 mg
Clone29F.1A12™IsotypeRat IgG2a
Applicationin vivo blocking of PD-1/PD-L signaling, in vitro PD-1 neutralization, Immunohistochemistry (frozen), Immunofluorescence, Western blot, Flow cytometry
RecommendedIsotype Control: BP0089 Dilution Buffer: IP0070
BP0274InVivoPlus anti-mouse TIGIT5/25/50/100 mg
Clone1G9IsotypeMouse IgG1, κ
Applicationin vivo TIGIT stimulation, Flow cytometry
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070
BP0310InVivoPlus anti-mouse VISTA5/25/50/100 mg
Clone13F3IsotypeArmenian Hamster IgG
Applicationin vivo blocking of VISTA signaling, in vitro blocking of VISTA signaling
RecommendedIsotype Control: BP0091 Dilution Buffer: IP0070

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InVivoSIM


SIM0003InVivoSIM anti-human PD-1 (Nivolumab Biosimilar)1/5/25/50/100 mg
CloneNivolumabIsotypeHuman IgG4
ApplicationBlocking of PD-1/PD-L signaling, Flow Cytometry, Immunohistochemistry, Western Blot
RecommendedIsotype Control: CP147 Dilution Buffer: IP0070
SIM0004InVivoSIM anti-human CTLA-4 (Ipilimumab Biosimilar)1/5/25/50/100 mg
CloneIpilimumabIsotypeHuman IgG1
ApplicationCTLA-4 neutralization, Flow Cytometry, ELISA, Western Blot
RecommendedIsotype Control: CP174 Dilution Buffer: IP0070
SIM0009InVivoSIM anti-human PD-L1 (Atezolizumab Biosimilar)1/5/25/50/100 mg
CloneAtezolizumabIsotypeHuman IgG1
ApplicationFlow Cytometry, Western Blot
RecommendedIsotype Control: CP171 Dilution Buffer: IP0070
SIM0010InVivoSIM anti-human PD-1 (Pembrolizumab Biosimilar)1/5/25/50/100 mg
ClonePembrolizumabIsotypeHuman IgG4
ApplicationBlocking of PD-1/PD-L signaling, Functional assays
RecommendedIsotype Control: CP147 Dilution Buffer: IP0070
SIM0015InVivoSIM anti-human LAG-3 (Relatlimab Biosimilar)1/5/25/50/100 mg
CloneRelatlimabIsotypeHuman IgG4, κ
ApplicationELISA
RecommendedIsotype Control: CP147 Dilution Buffer: IP0070
SIM0021InVivoSIM anti-human PD-L1 (Avelumab Biosimilar)1/5/25/50/100 mg
CloneAvelumabIsotypeHuman IgG1, λ
ApplicationFunctional assays, ELISA, in vitro PD-L1 blockade
RecommendedIsotype Control: CP169 Dilution Buffer: IP0070
SIM0027InVivoSIM anti-human PD-L1 (Durvalumab Biosimilar)1/5/25/50/100 mg
CloneDurvalumabIsotypeHuman IgG1, κ
ApplicationELISA, Flow Cytometry, Western Blot, Functional assays
RecommendedIsotype Control: CP149 Dilution Buffer: IP0070

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RecombiMAb


CP001RecombiMAb anti-mouse PD-L1 (B7-H1) (D265A)1 mg
Clone10F.9G2™-CP001IsotypeMouse IgG1, κ
Applicationin vivo PD-L1 blockade*, Immunofluorescence*, Immunohistochemistry (frozen)*, Flow cytometry*, Western blot*
*Reported for the original rat IgG2b 10F.9G2 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP002RecombiMAb anti-mouse PD-1 (CD279) (D265A)1 mg
CloneRMP1-14-CP002IsotypeMouse IgG1, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP004RecombiMAb anti-mouse PD-1 (CD279)1 mg
Clone29F.1A12™-CP004IsotypeMouse IgG1, κ
Applicationin vivo blocking of PD-1/PD-L signaling*, in vitro PD-1 neutralization*, Immunohistochemistry (frozen)*, Immunofluorescence*, Western blot*, Flow cytometry*
*Reported for the original rat IgG2a 29F.1A12 antibody
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070
CP005RecombiMAb anti-mouse PD-1 (CD279) (D265A)1 mg
Clone29F.1A12™-CP005IsotypeMouse IgG1, κ
Applicationin vivo blocking of PD-1/PD-L signaling*, in vitro PD-1 neutralization*, Immunohistochemistry (frozen)*, Immunofluorescence*, Western blot*, Flow cytometry*
*Reported for the original rat IgG2a 29F.1A12 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP006RecombiMAb anti-mouse CTLA-4 (CD152)1 mg
Clone9D9-CP006IsotypeMouse IgG1, κ
Applicationin vivo CTLA-4 neutralization*, Western blot*
*Reported for the original mouse IgG2b 9D9 antibody
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070
CP007RecombiMAb anti-mouse CTLA-4 (CD152)1 mg
Clone9D9-CP007IsotypeMouse IgG2a, κ
Applicationin vivo CTLA-4 neutralization*, Western blot*
*Reported for the original mouse IgG2b 9D9 antibody
RecommendedIsotype Control: BE0085 Dilution Buffer: IP0070
CP008RecombiMAb anti-mouse CTLA-4 (CD152) (LALA-PG)1 mg
Clone9D9-CP008IsotypeMouse IgG2a, κ
Applicationin vivo CTLA-4 neutralization*, Western blot*
*Reported for the original mouse IgG2b 9D9 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP013RecombiMAb anti-mouse LAG-3 (D265A)1 mg
CloneC9B7W-CP013IsotypeMouse IgG1, κ
Applicationin vivo LAG-3 neutralization*, in vitro LAG-3 neutralization*, Flow cytometry*, Western blot*
*Reported for the original rat IgG1 C9B7W antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP014RecombiMAb anti-mouse LAG-31 mg
CloneC9B7W-CP014IsotypeMouse IgG2a, κ
Applicationin vivo LAG-3 neutralization*, in vitro LAG-3 neutralization*, Flow cytometry*, Western blot*
*Reported for the original rat IgG1 C9B7W antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP017RecombiMAb anti-mouse OX40 (CD134)1 mg
CloneOX86-CP017IsotypeMouse IgG2a, κ
Applicationin vivo OX40 activation*, in vitro OX40 activation*, Western blot*
*Reported for the original rat IgG1 OX-86 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP018RecombiMAb anti-mouse OX40 (CD134) (LALA-PG)1 mg
CloneOX86-CP018IsotypeMouse IgG2a, κ
Applicationin vivo OX40 activation*, in vitro OX40 activation*, Western blot*
*Reported for the original rat IgG1 OX-86 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP027RecombiMAb anti-mouse GITR (D265A)1 mg
CloneDTA-1-CP027IsotypeMouse IgG1, κ
Applicationin vivo GITR stimulation*
*Reported for the original rat IgG2b DTA-1 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP028RecombiMAb anti-mouse GITR1 mg
CloneDTA-1-CP028IsotypeMouse IgG2a, κ
Applicationin vivo GITR stimulation*
*Reported for the original rat IgG2b DTA-1 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP029RecombiMAb anti-mouse GITR (LALA-PG)1 mg
CloneDTA-1-CP029IsotypeMouse IgG2a, κ
Applicationin vivo GITR stimulation*
*Reported for the original rat IgG2b DTA-1 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP031RecombiMAb anti-mouse GITR (LALA-PG)1 mg
CloneDTA-1-CP031IsotypeMouse IgG2b, κ
Applicationin vivo GITR stimulation*
*Reported for the original rat IgG2b DTA-1 antibody
RecommendedIsotype Control: CP049 Dilution Buffer: IP0070
CP032RecombiMAb anti-mouse CD40L (CD154) (D265A)1 mg
CloneMR-1-CP032IsotypeMouse IgG1, κ
Applicationin vivo blocking of CD40/CD40L signaling*, in vitro blocking of CD40/CD40L signaling*, Western blot*
*Reported for the original Armenian hamster IgG MR-1 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP033RecombiMAb anti-mouse CD40L (CD154)1 mg
CloneMR-1-CP033IsotypeMouse IgG2a, κ
Applicationin vivo blocking of CD40/CD40L signaling*, in vitro blocking of CD40/CD40L signaling*, Western blot*
*Reported for the original Armenian hamster IgG MR-1 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP034RecombiMAb anti-mouse CD40L (CD154) (LALA-PG)1 mg
CloneMR-1-CP034IsotypeMouse IgG2a, κ
Applicationin vivo blocking of CD40/CD40L signaling*, in vitro blocking of CD40/CD40L signaling*, Western blot*
*Reported for the original Armenian hamster IgG MR-1 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP038RecombiMAb anti-mouse 4-1BB (CD137) (LALA-PG)1 mg
CloneLOB12.3-CP038IsotypeMouse IgG2a, κ
Applicationin vivo activation of 4-1BB*
*Reported for the original rat IgG1 LOB12.3 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP039RecombiMAb anti-mouse 4-1BBL (CD137L) (D265A)1 mg
CloneTKS-1-CP039IsotypeMouse IgG1, κ
Applicationin vivo 4-1BBL blockade*, ELISA*
*Reported for the original rat IgG2a TKS-1 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP040RecombiMAb anti-mouse 4-1BBL (CD137L)1 mg
CloneTKS-1-CP040IsotypeMouse IgG2a, κ
Applicationin vivo 4-1BBL blockade*, ELISA*
*Reported for the original rat IgG2a TKS-1 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP041RecombiMAb anti-mouse 4-1BBL (CD137L) (LALA-PG)1 mg
CloneTKS-1-CP041IsotypeMouse IgG2a, κ
Applicationin vivo 4-1BBL blockade*, ELISA*
*Reported for the original rat IgG2a TKS-1 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP042RecombiMAb anti-mouse CD281 mg
CloneD665-CP042IsotypeMouse IgG2a, κ
Applicationin vivo T cell stimulation/activation*, in vitro T cell stimulation/activation*
*Reported for the original mouse IgG1 D665 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP043RecombiMAb anti-mouse CD28 (LALA-PG)1 mg
CloneD665-CP043IsotypeMouse IgG2a, κ
Applicationin vivo T cell stimulation/activation*, in vitro T cell stimulation/activation*
*Reported for the original mouse IgG1 D665 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP044RecombiMAb anti-mouse ICOSL (CD275) (D265A)1 mg
CloneHK5.3-CP044IsotypeMouse IgG1, κ
Applicationin vivo ICOSL neutralization*
*Reported for the original rat IgG2a HK5.3 antibody
RecommendedIsotype Control: CP047 Dilution Buffer: IP0070
CP045RecombiMAb anti-mouse ICOSL (CD275)1 mg
CloneHK5.3-CP045IsotypeMouse IgG2a, κ
Applicationin vivo ICOSL neutralization*
*Reported for the original rat IgG2a HK5.3 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP046RecombiMAb anti-mouse ICOSL (CD275) (LALA-PG)1 mg
CloneHK5.3-CP046IsotypeMouse IgG2a, κ
Applicationin vivo ICOSL neutralization*
*Reported for the original rat IgG2a HK5.3 antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP133RecombiMAb anti-mouse CD401/5/25/50/100 mg
CloneFGK4.5-CP133IsotypeMouse IgG2a, κ
Applicationin vivo CD40 activation*, in vitro B cell stimulation/activation*
*Reported for the original rat IgG2a FGK4.5 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP146RecombiMAb anti-mouse CTLA-4 (CD152)1/5/25/50/100 mg
Clone9H10-CP146IsotypeMouse IgG1, κ
Applicationin vivo CTLA-4 neutralization*, in vitro CTLA-4 neutralization*, Western blot, *Reported for the original Syrian hamster IgG 9H10 antibody
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070
CP151RecombiMAb anti-mouse PD-1 (CD279) (D265A)1/5/25/50 mg
CloneRMP1-14-CP151IsotypeMouse IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: CP150 Dilution Buffer: IP0070
CP151RecombiMAb anti-mouse PD-1 (CD279) (D265A)100 mg
CloneRMP1-14-CP151IsotypeMouse IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: CP150 Dilution Buffer: IP0070
CP153RecombiMAb anti-mouse PD-1 (CD279) (LALA-PG)1/5/25/50/100 mg
CloneRMP1-14-CP153IsotypeMouse IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: CP150 Dilution Buffer: IP0070
CP154RecombiMAb anti-mouse PD-L1 (B7-H1) (LALA-PG)1/5/25/50/100 mg
Clone10F.9G2™-CP154IsotypeMouse IgG2a, κ
Applicationin vivo PD-L1 blockade*, Immunofluorescence*, Immunohistochemistry (frozen)*, Flow cytometry*, Western blot*
*Reported for the original rat IgG2a 10F.9G2™ antibody
RecommendedIsotype Control: CP048 Dilution Buffer: IP0070
CP155RecombiMAb anti-mouse PD-1 (CD279) (LALA-PG)1/5/25/50/100 mg
Clone29F.1A12™-CP155IsotypeMouse IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling*, in vitro PD-1 neutralization*, Immunohistochemistry (frozen)*, Immunofluorescence*, Western blot*, Flow cytometry*
*Reported for the original rat IgG2a 29F.1A12 antibody
RecommendedIsotype Control: CP156 Dilution Buffer: IP0070
CP157RecombiMAb anti-mouse PD-1 (CD279)1/5/25/50/100 mg
CloneRMP1-14-CP157IsotypeMouse IgG2a, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: BP0085 Dilution Buffer: IP0070
CP160RecombiMAb mouse IgG2a isotype control, unknown specificity1/5/25/50/100 mg
CloneMOPC-21-CP160IsotypeMouse IgG1, κ
Applicationin vivo LAG-3 neutralization*, in vitro LAG-3 neutralization*, Flow cytometry*, Western blot*
*Reported for the original rat IgG1 C9B7W antibody
RecommendedDilution Buffer: IP0070
CP162RecombiMAb anti-mouse PD-1 (CD279)1/5/25/50/100 mg
CloneRMP1-14-CP162IsotypeMouse IgG1, κ
Applicationin vivo blocking of PD-1/PD-L signaling*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070
CP168RecombiMAb anti-mouse PD-L1 (B7-H1)1/5/25/50/100 mg
Clone10F.9G2™-CP168IsotypeMouse IgG1, κ
Applicationin vivo PD-L1 blockade*, Immunofluorescence*, Immunohistochemistry (frozen)*, Flow cytometry*, Western blot*
*Reported for the original rat IgG2a RMP1-14 antibody
RecommendedIsotype Control: BP0083 Dilution Buffer: IP0070

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